Synthesis of new beta-hydroxy nitrate esters as potential glycomimetics or vasodilators

Çavdar H., SARAÇOĞLU N.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, sa.27, ss.4615-4621, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1002/ejoc.200800481
  • Dergi Adı: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4615-4621
  • Anahtar Kelimeler: cyclitols, epoxidation, nucleophilic addition, ring expansion, Lewis acids, STABLE ANGINA-PECTORIS, CERIC AMMONIUM-NITRATE, NITRIC-OXIDE, AROMATIC-AMINES, GLYCOSIDASE INHIBITORS, HOMOALLYLIC ALCOHOLS, BIOLOGICAL-ACTIVITY, EFFICIENT METHOD, CARBA-SUGARS, EPOXIDES
  • Atatürk Üniversitesi Adresli: Evet

Özet

New beta-hydroxy nitrates have been synthesized by the ring-opening reaction of epoxides with Bi(NO3)(3)center dot 5H(2)O, which was used both as a catalyst and reagent. The synthesized molecules are both potential cyclitol mimetics and vasodilators as a result of their hydroxy groups and nitrate esters. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).