TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.28, sa.4, ss.569-571, 2008 (SCI-Expanded)
Drug-induced esophagitis is a rare complication of certain drugs including antibiotics and anti-inflammatory agents used in medical therapy. A 28 year-old woman presented to our hospital with an acute onset severe retrosternal pain, odynophagia and dysphagia after using doxycycline for her genital infection. Her history included drug ingestion with a small amount of water. Endoscopic examination detected deep ulcerations at the middle third of esophagus. Apparent improvement in her symptoms started 3 days after initiation of omeprazole following discontinuation of doxycycline. Pills are a preventable cause of esophageal injury. Drug-induced esophagitis is not uncommon with certain drugs and use of this drug should be investigated in patients presenting with retrosternal pain.