The Status of Bovine Viral Diarrhea Virus (BVDV) in Western Türkiye: Detection of Three Subtypes


ÇAĞIRGAN A. A., KAPLAN M., PEKMEZ K., VAN SCHALKWYK A., ARSLAN F., TİMURKAN M. Ö.

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.28, sa.6, ss.709-715, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 6
  • Basım Tarihi: 2022
  • Doi Numarası: 10.9775/kvfd.2022.27881
  • Dergi Adı: KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.709-715
  • Anahtar Kelimeler: Abortion, Bovine viral diarrhea virus, Cattle, Genetic variation, Turkiye, MOLECULAR CHARACTERIZATION, GENETIC DIVERSITY, CATTLE, PESTIVIRUSES, IDENTIFICATION, HETEROGENEITY, GENOTYPE-1, REGION, TURKEY, P125
  • Atatürk Üniversitesi Adresli: Evet

Özet

Bovine viral diarrhea virus (BVDV) is a viral pathogen that causes significant economic losses in cattle, especially by causing abortions. Globally, BVDVs are classified into three genetically distinct types: BVDV-1, BVDV-2 and BVDV-3. Despite the presence of all three groups in Turkiye, BVDV-1 is by far the most prevalent. The aim of the study was to determine the genetic diversity of BVDV detected in materials from aborted fetus between 2017 and 2020 in western Turkiye. Sequence and phylogenetic analyzes were performed based on the 5'-UTR and Npro gene regions of BVDVs from samples, which tested positive using real time RT-PCR. According to pairwise similarity and cluster analysis the samples clustered into three different sub-types, with one dominant subtype 1d (n=4). The remaining samples clustered within subtype 1l (n=3) and 1f (n=2). In this study, different subtypes were found in abortion materials submitted from the same region. Since different subtypes of BVDV were identified even in a small geographical area of Turkiye, it is essential to prepare control and eradication programs through specific vaccination, diagnostic and mitigation programs coordinated by national government, to prevent the spread of these viruses.