A new marker for the prediction of contrast induced-acute kidney injury following primary percutaneous coronary intervention: logarithm of haemoglobin–albumin product

Özveren O., Tanalp A. C., Tanboğa İ. H., Karagöz A., Saygı M., BİRDAL O., ...Daha Fazla

Acta Cardiologica, cilt.78, sa.8, ss.901-909, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 8
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1080/00015385.2023.2187126
  • Dergi Adı: Acta Cardiologica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.901-909
  • Anahtar Kelimeler: Hemoglobin, creatinine, acute kidney injury, myocardial infarction, albumin, morbidity, ACUTE-RENAL-FAILURE, ELEVATION MYOCARDIAL-INFARCTION, SERUM-ALBUMIN, INDUCED NEPHROPATHY, RISK-FACTORS, CARDIOVASCULAR-DISEASE, REQUIRING DIALYSIS, TERM OUTCOMES, HEART-DISEASE, IMPACT
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Contrast-induced acute kidney injury (CI-AKI) is a disorder that adversely affects the prognosis of STEMI. The study aimed to assess the predictive value of a new marker, logarithm of haemoglobin and albumin product (LHAP) on the risk of CI-AKI development after primary percutaneous coronary intervention (p-pcı). Method: We retrospectively enrolled 3057 patients with ST-elevation acute myocardial infarction who were treated with p-PCI. The primary outcome was CI-AKI, defined as >25% or >0.5 mg/dl increase of baseline creatinine values during post-procedural 48 h. Results: First, a baseline model was produced to determine the predictors of CI-AKI, then haemoglobin, albumin and LHAP were included in the base model and the performances of all models were compared. The predictive accuracy (Likelihood ratio χ 2 and R 2) and discrimination (ROC-AUC) of the model including LHAP were significantly higher than that of models including both albumin and Hgb. LHAP best cut-off value for the development of CI-AKI was 9.26 (sensitivity 68% and specificity 66%). Conclusion: LHAP values were the most important predictor of CI-AKI, followed by creatinine value and Killip class. LHAP values are significantly associated with CI-AKI after p-PCI.