A New Target in Inflammatory Diseases: Lycopene

KARAKÖY Z., ÇADIRCI E., Dincer B.

EURASIAN JOURNAL OF MEDICINE, cilt.54, 2022 (ESCI) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 54
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/eurasianjmed.2022.22303
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Anahtar Kelimeler: Lycopene, free radicals, inflammation, ALPHA-LIPOIC ACID, NF-KAPPA-B, OXIDATIVE STRESS, ACUTE-PANCREATITIS, CROHNS-DISEASE, ANTIOXIDANT, APOPTOSIS, PROTECTS, INJURY, MODEL
  • Atatürk Üniversitesi Adresli: Evet

Özet

Inflammation is a response to various injuries, illnesses, and severe trauma. The primary function of inflammation is to combat pathogens, eliminate them from the body, and initiate wound healing. However, inflammation also contributes to numerous diseases, such as cancer, cardiovascular disease, diabetes, obesity, osteoporosis, rheumatoid arthritis, inflammatory bowel disease, and asthma. As the importance of nutrition in maintaining human health has become increasingly recognized, the consumption of natural antioxidants has gained popularity, especially in developed countries. A growing body of research has shown that consuming foods rich in lycopene can protect individuals from a range of conditions, including cancer, heart disease, and other diseases. As a result, lycopene is gaining recognition as a potential protective antioxidant in the fields of medicine and pharmacology. This review aims to highlight the effects of lycopene on inflammatory diseases and provide a foundational understanding for researchers interested in further research on lycopene.