Vitamin D and inflammation: evaluation with neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio

AKBAŞ E. M., Gungor A., ÖZÇİÇEK A., AKBAŞ N., AŞKIN S., Polat M.

ARCHIVES OF MEDICAL SCIENCE, cilt.12, sa.4, ss.721-727, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5114/aoms.2015.50625
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.721-727
  • Anahtar Kelimeler: vitamin D, inflammation, endothelial dysfunction, C-REACTIVE PROTEIN, EPICARDIAL ADIPOSE-TISSUE, SERUM 25-HYDROXYVITAMIN D, CARDIOVASCULAR-DISEASE, D SUPPLEMENTATION, D DEFICIENCY, SYSTEMIC INFLAMMATION, ENDOTHELIAL FUNCTION, ASSOCIATION, PLASMA
  • Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: Association of vitamin D, inflammation and endothelial dysfunction, beside the classic bone metabolism disorders, may explain the pathogenesis of numerous diseases associated with vitamin D deficiency. While large numbers of reports support the relationship of vitamin D with inflammation, several reports fail to confirm this relationship. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are novel and inexpensive markers of inflammation that can be studied in all centers. The goal of this study was to investigate the association between 25-hydroxy vitamin D (25(OH) D) and inflammation with the novel inflammatory markers NLR and PLR.