Atıf İçin Kopyala
Naldan M. E., TAGHIZADEHGHALEHJOUGHI A.
BRAZILIAN JOURNAL OF ANESTHESIOLOGY, cilt.71, sa.4, ss.402-407, 2021 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
71
Sayı:
4
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Basım Tarihi:
2021
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Doi Numarası:
10.1016/j.bjane.2021.04.003
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Dergi Adı:
BRAZILIAN JOURNAL OF ANESTHESIOLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Directory of Open Access Journals
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Sayfa Sayıları:
ss.402-407
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Anahtar Kelimeler:
Remifentanil, Olfactory bulb neuron, Glutamate, Neurotoxicity, D-ASPARTATE RECEPTOR, NMDA RECEPTOR, HYPERALGESIA, EXCITOTOXICITY, STRESS
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Atatürk Üniversitesi Adresli:
Evet
Özet
Background: Opioids are widely used as an analgesic drug in the surgical setting. Remifentanil is an ultra-short acting opioid with selective affinity to the mu GO receptor, and also exhibits GABA agonist effects. The aim of this study was study of the neurotoxic or neuroprotective effect of different doses of remifentanil in glutamate-induced toxicity in olfactory neuron cell culture.