Postpartum Lactation Failure Secondary to Isolated Prolactin Deficiency: A Case Report and Literature Review


BİLEN A., BİLEN H., GÜNGÖR ALBAYRAK E., KARADENİZ Y., GÖKKAYA N.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.26, sa.2, ss.97-99, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 26 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/tjem.2022.22048
  • Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.97-99
  • Anahtar Kelimeler: Hormone deficiency, isolated prolactin deficiency, lactation, lactation failure, r-hPRL, WOMAN
  • Atatürk Üniversitesi Adresli: Evet

Özet

Prolactin deficiency can occur alone, as can be seen by the deficiency of 1 or more of the other ante-rior pituitary hormones. Isolated prolactin deficiency is an extremely rare condition, and the only known symptom is the lack of lactation in postpartum women. A 29-year-old female presented in 2 weeks postpartum for evaluation of lactation failure. On the postpartum 16th day, the prolactin level was very low. Since there were no other pituitary abnormalities, we considered the diagnosis of isolated prolactin deficiency. In this case, we presented lactation failure due to isolated prolactin defi-ciency, which is extremely rare in the literature. In isolated prolactin deficiency, most of the patients are diagnosed with the absence of lactation and there are no other concurrent pituitary pathologies. In the treatment, recombinant human prolactin stands out as an option, but it is unavailable in many countries. In most cases, baby formula is used to feed babies.