Investigation of CYP2E1 and Caspase-3 Gene Expressions in COVID-19 patients

Uzuncakmak S. K., Dirican E., Naldan M. E., KESMEZ CAN F., Hallcl Z.

GENE REPORTS, cilt.26, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1016/j.genrep.2022.101497
  • Dergi Adı: GENE REPORTS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, BIOSIS, EMBASE
  • Anahtar Kelimeler: CCYP2E1, COVID-19, Caspase-3, SARS-CoV-2, MITOCHONDRIAL DYSFUNCTION, OXIDATIVE STRESS, LIVER-INJURY, CYTOCHROME-P450, ALCOHOL, DEATH, CELLS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: COVID-19 pandemic spread around the world like an infectious disease that presents waved effects on patients. Some patients needed ICU and respiratory support. Some patients only had flu-like symptoms. Cytokine storm and elevated ROS were serious problems for treatment. Apoptotic genes and CYP Family are part of these mechanisms.