Evaluation of the Relationship Between Diabetic Retinopathy and the Development of Left Atrial Stiffness in Patients with Diabetes Mellitus


BİRDAL O., Saygı M., Doğan R., Pay L., Aksakal E., Topaloğlu C., ...Daha Fazla

Eurasian Journal of Medicine, cilt.55, sa.3, ss.249-253, 2023 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 3
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5152/eurasianjmed.2023.23235
  • Dergi Adı: Eurasian Journal of Medicine
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.249-253
  • Anahtar Kelimeler: Diabetes mellitus, LA stiffness, MAPSE, retinopathy
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: Based on several studies, atrial remodeling results in an increase in left atrial (LA) stiffness, which is indicative of a worsened reservoir function. A typical microvascular consequence of diabetes mellitus (DM) is diabetic retinopathy. Therefore, the objective of this study was to assess the factors that might be related to LA stiffness in DM patients. Materials and Methods: There were 200 DM patients in the study population. The LA stiffness value of 0.33 led to the division of the patients into 2 groups. According to these groups, the parameters to predict the development of the LA stiffness were investigated. Results: The patient population’s median age was 54.7 ± 9.4 years, and of them, 105 (52.5% of the population) were men. Retinopathy was substantially linked with LA stiffness. Interventricular septum thickness (B coefficient: 0.261, 95% CI 0.128; 0.394; P <.001), mitral annular plane systolic excursion (B coefficient: −0.350, 95% CI −0.489; −0.2212; P < 0.001), and retinopathy (B coefficient: 0.644, 95% CI 0.307; 0.983; P <.001) were identified as independent predictors of the progression of LA stiffness by the linear regression model. Conclusion: The results of the current investigation demonstrated a correlation between higher LA stiffness values and the presence of diabetic retinopathy in diabetic patients.