How to set up a molecular pathology lab: a guide for pathologists


AYSAL AĞALAR A., Pehlivanoğlu B., Ekmekçi S., GÜNDOĞDU B.

Turkish Journal of Pathology, cilt.36, sa.3, ss.179-187, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 36 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5146/tjpath.2020.01488
  • Dergi Adı: Turkish Journal of Pathology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.179-187
  • Anahtar Kelimeler: Guide, Laboratory setup, Molecular pathology laboratory
  • Atatürk Üniversitesi Adresli: Evet

Özet

In today's pathology practice, pathologists combine molecular tests with conventional histopathological methods. Pathology laboratories should therefore be designed and operated in accordance with the requirements of molecular testing procedures. While the specifics of the requirements may vary depending on the spectrum of the tests that will be performed, there are several basic criteria that need to be fulfilled for standardization. Adequate space, appropriate equipment and qualified personnel are required to establish a molecular pathology laboratory. One of the most important points that should be taken into consideration while designing a molecular pathology laboratory is to create a plan to prevent contamination. As molecular diagnosis has a major role in treatment decisions, the management of the molecular pathology laboratory is of utmost importance. In this review, the criteria required to establish an optimal molecular pathology laboratory will be reviewed.