Naphthoquinones from the roots of Onosma argentatum Hub.-Mor. (Boraginaceae)

ÖZGEN U., COŞKUN M., Kazaz C., Secen H.

TURKISH JOURNAL OF CHEMISTRY, cilt.28, sa.4, ss.451-454, 2004 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2004
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.451-454
  • Anahtar Kelimeler: Onosma argentatum, natural naphthoquinones, shikonin derivatives, Boraginaccae, 5,8-O-dimethyl acetyl shikonin, ANTIMICROBIAL ACTIVITIES, PYRROLIZIDINE ALKALOIDS, DERIVATIVES
  • Atatürk Üniversitesi Adresli: Evet

Özet

Onosma argentatum Hub.-Mor. is an endemic species growing in Turkey. In this study, the roots of O. argentatum were extracted with n-hexane-dichloromethane (1:1). The extract was separated on a silica gel column eluting with n-hexane-ethyl acetate by gradient elution. New naphthoquinone compounds (3 known and 1 new) were isolated and their structures were elucidated by spectroscopic methods as deoxyshikonin, acetyl shikonin, 3-hydroxy-isovaleryl shikonin, and 5,8-O-dimethyl acetyl shikonin.