The relationship between inflammation and hematological parameters in chronic kidney disease


Demirci R., SEVİNÇ C., Şanlı K.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.12, sa.5, ss.592-596, 2021 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4328/acam.20642
  • Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.592-596
  • Anahtar Kelimeler: Hemogram, Inflammation, CKD, Proteinuria, NEUTROPHIL-TO-LYMPHOCYTE, CARDIOVASCULAR-DISEASE, CLINICAL-OUTCOMES, PROTEINURIA, RATIO, ASSOCIATION, RISK, COUNT
  • Atatürk Üniversitesi Adresli: Evet

Özet

Aim: The progression of Chronic Kidney Disease (CKD) is closely related to systemic inflammation and oxidative stress. This situation causes malnutrition, atherosclerosis, coronary artery calcification, heart failure, anemia, mineral and bone disorders, increasing mortality and morbidity. An increased number of leukocytes and their subtypes is a feature of the inflammatory process. The neutrophil-lymphocyte ratio (NLR), derived from leukocyte counts has been shown to be a strong indicator of acute and chronic inflammation, associated with cardiovascular risk. In our study, it was aimed to investigate the relationship between hematological parameters and Glomerular Filtration Rate (GFR) and proteinuria, which is an indicator of inflammation, in patients with CKD stage 3-5 without dialysis treatment.