Akademik Veri Yönetim Sistemi
ISRAEL JOURNAL OF VETERINARY MEDICINE, cilt.67, sa.2, ss.127-131, 2012 (SCI-Expanded)
This study reports the histopathological and immunohistochemical finding of a congenital choroid plexus papilloma in a newborn calf Macroscopically, the mass protruded from the parietal bone and resembled the shape of a cauliflower. The tumor was 6.2 x 5 x 7.3 cm in size, pinkish in color and contained patches of hemorrhage. Histopathological examination revealed the presence of well-differentiated papillary structures of cuboidal and columnar epithelial cells enclosed by a fibrovascular stroma exhibiting branching arbiriform pattern. The tumor cells were generally large and contained brightly eosinophilic granular cytoplasm with central nuclei. There was only mild nuclear pleomorphism and mitosis was rare. The tumor cells gave positive results for pancytokeratin, S100, vimentin and the epithelial membrane antigen (EMA), but did not stain with glial fibrillary acidic protein (GFAP).