GC-MS Determination of Diclofenac in Human Plasma

Yilmaz B.

CHROMATOGRAPHIA, cilt.71, ss.549-551, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 71
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1365/s10337-010-1479-z
  • Dergi Adı: CHROMATOGRAPHIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.549-551
  • Anahtar Kelimeler: Gas chromatography-mass spectrometry, Diclofenac in human, Plasma, LIQUID-CHROMATOGRAPHIC DETERMINATION, ELECTROCHEMICAL DETECTION, METABOLITES, URINE, BIOAVAILABILITY, FLUID
  • Atatürk Üniversitesi Adresli: Evet

Özet

The aim of the present study was to develop a procedure based on gas chromatography-mass spectrometry for the determination of diclofenac in human plasma. This assay was successfully applied in Turkey to healthy volunteers after an oral administration of 50 mg diclofenac.