Akademik Veri Yönetim Sistemi
Akademik Gastroenteroloji Dergisi, cilt.20, sa.1, ss.3-7, 2021 (Hakemli Dergi)
Background and Aims: Approximately 75-90% of gastric polyps are
comprised of hyperplastic polyps formed by precursor lesions after foveolar hyperplasia and chronic gastritis due to excessive epithelial regeneration caused by chronic inflammation. In this study, we discuss the
relationship between gastric hyperplastic polyps and precursor lesions
and Helicobacter pylori as well as intestinal metaplasia and the atrophy
states of these lesions in light of the literature. Material and Methods:
Among 7,903 patients who underwent esophagogastroduodenoscopy at Muş State Hospital between January 2016 and January 2020,
172 with an endoscopic view of polypoid structures were included and
histopathologically examined. Data including age, sex, admission complaint, location of the polypoid lesion, and histopathological type were
recorded. Results: The patients [101 females (58.8%); age, 49.4 ± 15
(19–83) years] underwent polypectomy. They were divided into the
reactive polypoid group (57 patients with reactive foveolar hyperplasia
and 53 with reactive chronic gastritis) and the actual polypoid group
(62 patients; hyperplastic polyps in 47). Polypoid lesions were most often localized in the antrum. The most common complaint on admission
was dyspepsia. The diameter of the actual polypoid lesions was significantly larger than that of the reactive polypoid lesions (p < 0.05).
The rate of Helicobacter pylori infection was significantly higher in the
reactive polypoid group than in the actual polyploid group (p < 0.05).
There was no difference in terms of intestinal metaplasia and atrophy
(p > 0.05). Conclusions: No significant differences were observed in
the prevalence of intestinal metaplasia and atrophy or between the
rates of atrophy and intestinal metaplasia (precancerous condition of
the hyperplastic polyps and their precursor lesions). Therefore, biopsy
or excision of endoscopically detected lesions should be performed to
diagnose dysplasia. Patients should be treated for Helicobacter pylori.
Key words: Hyperplastic polyp, foveolar hyperplasia, chronic gastritis,
Helicobacter pylori