Should Increased Levels of Urinary 8-Hydroxydeoxyguanosine in Chronic Gastritis Imply Intestinal Metaplasia or Gastric Atrophy?

ALBAYRAK F., Uyanik M. H., Dursun H., Albayrak Y., Altas S., Uyanik A., ...Daha Fazla

SOUTHERN MEDICAL JOURNAL, cilt.103, sa.8, ss.753-757, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103 Sayı: 8
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1097/smj.0b013e3181e6d55d
  • Dergi Adı: SOUTHERN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.753-757
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objectives: Helicobacter pylori (H pylori) infection induces chronic inflammation that can progress to gastric atrophy, intestinal metaplasia, and gastric adenocarcinoma. We have examined oxidative damage caused by Helicobacter pylori, metaplasia, and atrophy of gastric mucosal cells in patients with chronic gastritis by measuring their urinary 8-hydroxydeoxyguanosine (8-OHdG) levels.