The efficacy of aripiprazole in treatment-resistant Tourette's syndrome: A case report


Fidan T., TAN H., Ceyhun H. A.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.19, 2009 (SCI-Expanded) identifier

Özet

Objective: Tourette's syndrome (TS) is an important childhood-onset neuropsychiatric disorder that is characterized by non-rhythmic, sudden, rapid, involuntary, repetitive multiple motor tics and at least one vocal (phonic) tic. Ideal anti-tit treatments are not presently available. Several typical neuroleptics frequently used for treatment of TS,have potentially serious side-effects. To report a lasting improvement obtained with a new drug, aripiprazole that acts modulating both dopaminergic and serotaninergic neurotransmission. A search of literature reveals data on aripiprazole's use in the adult population with limited research in the child and adolescent age group. In this case report, we aim to share our experience with patient with Tourette's Syndrome, who had persistent symptoms despite the use of at least one psychotropic agent. We also aim to provide data on the efficacy of aripiprazole in Tourette's Syndrome in addition to its use in adolescent age group.