Evaluation of alpha defensin, IL-1 receptor antagonist, and IL-18 levels in COVID-19 patients with macrophage activation syndrome and acute respiratory distress syndrome


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Kerget B. , Kerget F., Aksakal A., Aşkın S. , Sağlam L., Akgün M.

JOURNAL OF MEDICAL VIROLOGY, vol.93, no.4, pp.2090-2098, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 93 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.1002/jmv.26589
  • Title of Journal : JOURNAL OF MEDICAL VIROLOGY
  • Page Numbers: pp.2090-2098
  • Keywords: alpha defensin, COVID-19, IL-18, IL-1Ra, VIRUS

Abstract

Background Many laboratory parameters have been associated with morbidity and mortality in SARS-CoV-2 (COVID-19), which emerged in an animal market in Wuhan, China in December 2019 and has infected over 20 million people. This study investigated the relationship between serum interleukin (IL)-18, IL-1 receptor antagonist (IL-1Ra), and alpha defensin levels and the clinical course and prognosis of COVID-19.