The relationship between Vitamin D, autistic spectrum disorders, and cognitive development: do glial cell line-derived neurotrophic factor and nerve growth factor play a role in this relationship ?

Ucuz I. I., Dursun O. B., ESİN İ. S., ÖZGERİŞ F. B., Kurt N., KIZILTUNÇ A., ...Daha Fazla

INTERNATIONAL JOURNAL OF DEVELOPMENTAL DISABILITIES, cilt.61, sa.4, ss.222-230, 2015 (SSCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1179/2047387714y.0000000054
  • Dergi Adı: INTERNATIONAL JOURNAL OF DEVELOPMENTAL DISABILITIES
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.222-230
  • Anahtar Kelimeler: Vitamin D, developmental delay, autism, NGF, GDNF, 1,25-DIHYDROXYVITAMIN D-3, DIFFERENTIAL REGULATION, CHILDREN, GDNF, PREVALENCE, DEFICIENCY, 25-HYDROXY, EXPRESSION, GENE
  • Atatürk Üniversitesi Adresli: Evet

Özet

Objective: In recent years, there has been an increasing interest in the effects of Vitamin D on cognitive development and autism. The aim of this study is to examine the relationship between autism, cognitive developmental delay and behavioral problems. We also aimed to examine the possible mechanisms of interaction between nerve growth factor (NGF) and glial cell line-derived neurotrophic factor (GDNF) levels.