Antidepressant-like effects of ceftriaxone in chronic unpredictable mild stress model in rats: The importance of reuptake time of glutamate

Binnetoğlu D., Arıcıoğlu F., Özcan H., Okkay U., Hacımüftüoğlu A.

Clinical and Experimental Health Sciences, cilt.9, ss.294-299, 2019 (TRDizin)

Özet

Objective: We aimed to indicate the relationship between depression and glutamate, and to reveal the effect of escitalopram, an antidepressant, which is widely used in depression treatment and reuptake parameters of glutamate, and to treat depression with ceftriaxone, one of the beta lactam antibiotics which increased the number and activity of glutamate transporters.