Sister chromatid exchange and micronucleus studies in patients with Behcet's disease

Karaman A., Kadi M., KARA F.

JOURNAL OF CUTANEOUS PATHOLOGY, cilt.36, sa.8, ss.831-837, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 8
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1600-0560.2008.01180.x
  • Dergi Adı: JOURNAL OF CUTANEOUS PATHOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.831-837
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: Genetic factors that predispose individuals to Behcet's disease (BD) are considered to play important roles in the development of the disease. The aim of this study was to determine, by counting sister chromatid exchange (SCE) and micronucleus (MN) frequencies, whether DNA damage have an effect on the pathogenesis of BD. Furthermore, our aim was to show if there is an association between oxidative stress and chromosome instability in BD.