The relationship of telmisartan with sclerostin in the osteoporosis model induced by ovariectomy in rats


KUTLU Z. , BİLEN A. , ÇELİK M. , MAMAN A. , GÜLABOĞLU M. , KUL A. , ...More

JOURNAL OF PHARMACY AND PHARMACOLOGY, vol.73, no.12, pp.1693-1702, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.1093/jpp/rgab123
  • Title of Journal : JOURNAL OF PHARMACY AND PHARMACOLOGY
  • Page Numbers: pp.1693-1702
  • Keywords: angiotensin II receptor, osteocalcin, osteoporosis, sclerostin, tartrate-resistant acid phosphatase, BONE TURNOVER MARKERS, ANGIOTENSIN-II, SERUM SCLEROSTIN, MINERAL DENSITY, RECEPTOR, EPIDEMIOLOGY, HYPERTENSION, INHIBITION, BIOLOGY, DAMAGE

Abstract

Objectives Our aim is to explain the relationship between Ang II and Scl in osteoporotic (OP) rats and the contribution of Scl in the antiosteoporotic effect mechanism of angiotensin receptor blockers (ARB).