The relationship of telmisartan with sclerostin in the osteoporosis model induced by ovariectomy in rats

KUTLU, Zerrin; BİLEN, Arzu; ÇELİK, Muhammet; MAMAN, Adem; GÜLABOĞLU, Mine; KUL, Ayhan; Celik, Zeynep; HALICI, Zekai

doi:10.1093/jpp/rgab123

The relationship of telmisartan with sclerostin in the osteoporosis model induced by ovariectomy in rats

KUTLU Z. , BİLEN A. , ÇELİK M. , MAMAN A. , GÜLABOĞLU M. , KUL A. , ...More

JOURNAL OF PHARMACY AND PHARMACOLOGY, vol.73, no.12, pp.1693-1702, 2021 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 73 Issue: 12
Publication Date: 2021
Doi Number: 10.1093/jpp/rgab123
Title of Journal : JOURNAL OF PHARMACY AND PHARMACOLOGY
Page Numbers: pp.1693-1702
Keywords: angiotensin II receptor, osteocalcin, osteoporosis, sclerostin, tartrate-resistant acid phosphatase, BONE TURNOVER MARKERS, ANGIOTENSIN-II, SERUM SCLEROSTIN, MINERAL DENSITY, RECEPTOR, EPIDEMIOLOGY, HYPERTENSION, INHIBITION, BIOLOGY, DAMAGE

Abstract

Objectives Our aim is to explain the relationship between Ang II and Scl in osteoporotic (OP) rats and the contribution of Scl in the antiosteoporotic effect mechanism of angiotensin receptor blockers (ARB).