Therapeutic effects of oleuropein on cisplatin-induced pancreas injury in rats


BAKIR M., GEYİKOĞLU F. , KOÇ K. , Cerig S.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, vol.14, no.3, pp.671-678, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.4103/jcrt.jcrt_1040_16
  • Title of Journal : JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
  • Page Numbers: pp.671-678

Abstract

Aims: Cisplatin (CIS) is an influential chemotherapeutic agent in the treatment of several types of malignant solid tumors, but its clinical use is related with ototoxicity. Oleuropein (OLE) is a natural antioxidant and scavenging free radicals. Here, we first explore the efficacy of OLE in pancreas against to the toxicity of CIS and also analyses its mechanism.