Hypoglycaemic effect of Artemisia herba-alba in experimental hyperglycaemic rats


Tastekin D., Atasever M. , Adiguzel G. , Keles M., Tastekin A.

Bulletin of the Veterinary Institute in Pulawy, vol.50, no.2, pp.235-238, 2006 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2006
  • Title of Journal : Bulletin of the Veterinary Institute in Pulawy
  • Page Numbers: pp.235-238

Abstract

Artemisia herba-alba was investigated for its possible anti-diabetic effect in alloxan-induced diabetic rats. Oral administration of 0.39 g/kg b.w. of the aqueous Solution of Artemisia herba-alba exhibited a significant reduction in blood glucose content. The same effect was also seen after administration of repaglinide (1 mg/kg bw.) and regular insulin (0.1 IU/kg b.w.). It was demonstrated that the anti-diabetic effect of Artemisia herba-alba was similar to that of repaglinide and regular insulin. These results suggest that the Artemisia herba-alba possesses antidiabetic activity and is able to ameliorate biochemical damages in alloxan induced diabetes in rats.