Hypoglycaemic effect of Artemisia herba-alba in experimental hyperglycaemic rats
Bulletin of the Veterinary Institute in Pulawy, cilt.50, sa.2, ss.235-238, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 2
- Basım Tarihi: 2006
- Dergi Adı: Bulletin of the Veterinary Institute in Pulawy
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.235-238
- Anahtar Kelimeler: rats, Artemisia herba-alba, hypoglycaemia, hyperglycaemia, alloxan, diabetes, mellitits
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Atatürk Üniversitesi Adresli: Evet
Özet
Artemisia herba-alba was investigated for its possible anti-diabetic effect in alloxan-induced diabetic rats. Oral administration of 0.39 g/kg b.w. of the aqueous Solution of Artemisia herba-alba exhibited a significant reduction in blood glucose content. The same effect was also seen after administration of repaglinide (1 mg/kg bw.) and regular insulin (0.1 IU/kg b.w.). It was demonstrated that the anti-diabetic effect of Artemisia herba-alba was similar to that of repaglinide and regular insulin. These results suggest that the Artemisia herba-alba possesses antidiabetic activity and is able to ameliorate biochemical damages in alloxan induced diabetes in rats.