Modeling operon dynamics: the tryptophan and lactose operons as paradigms

Mackey M., Santillan M., Yildirim N.

COMPTES RENDUS BIOLOGIES, cilt.327, sa.3, ss.211-224, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 327 Sayı: 3
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.crvi.2003.11.009
  • Dergi Adı: COMPTES RENDUS BIOLOGIES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.211-224
  • Anahtar Kelimeler: gene regulatory networks, nonlinear dynamics, computational molecular biology, ESCHERICHIA-COLI, BETA-GALACTOSIDASE, INDUCER EXCLUSION, PHOSPHOENOLPYRUVATE, BIFURCATION, INHIBITION, GLUCOSE, GROWTH
  • Atatürk Üniversitesi Adresli: Hayır

Özet

Understanding the regulation of gene control networks and their ensuing dynamics will be a critical component in the understanding of the mountain of genomic data being currently collected. This paper reviews recent mathematical modeling work on the tryptophan and lactose operons which are, respectively, the classical paradigms for repressible and inducible operons. (C) 2004 Published by Elsevier SAS on behalf of Academie des sciences.