Comparative Study on Effects of Nebulized and Oral Salbutamol on a Cecal Ligation and Puncture-Induced Sepsis Model in Rats

OZOGUL, Bünyami; Halici, Zekai; CADIRCI, Elif; KARAGOZ, E; BAYRAKTUTAN, Zafer; YAYLA, Mansur; AKPINAR, Erol; ATAMANALP, Sabri; UNAL, Deniz; KARAMESE, M

doi:10.1055/s-0034-1375683

Comparative Study on Effects of Nebulized and Oral Salbutamol on a Cecal Ligation and Puncture-Induced Sepsis Model in Rats

OZOGUL B., Halici Z., CADIRCI E., KARAGOZ E., BAYRAKTUTAN Z., YAYLA M., ...Daha Fazla

DRUG RESEARCH, cilt.65, sa.4, ss.192-198, 2015 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 65 Sayı: 4
Basım Tarihi: 2015
Doi Numarası: 10.1055/s-0034-1375683
Dergi Adı: DRUG RESEARCH
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.192-198
Anahtar Kelimeler: salbutamol, beta-adrenergic receptor, sepsis, cytokine, oxidative stress, rat, RESPIRATORY-DISTRESS-SYNDROME, TUMOR-NECROSIS-FACTOR, INCREASED GENE-EXPRESSION, PROINFLAMMATORY CYTOKINES, LUNG INJURY, HEPATOCELLULAR DYSFUNCTION, POLYMICROBIAL SEPSIS, OVARIECTOMIZED RATS, ANTIOXIDANT ENZYMES, LIPID-PEROXIDATION
Atatürk Üniversitesi Adresli: Evet

Özet

Aim: The present study aimed to compare the effects of different routes of salbutamol administration (oral and nebulized) at different doses in a cecal ligation and puncture-induced (CLP-induced) sepsis model of rats.