The Effects of Agomelatine Treatment on Lipopolysaccharide-Induced Septic Lung Injuries in Rats

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KÖSE D., Yuksel T. N., HALICI Z., ÇADIRCI E., GÜRBÜZ M. A.

EURASIAN JOURNAL OF MEDICINE, vol.53, no.2, pp.127-131, 2021 (ESCI, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 53 Issue: 2
• Publication Date: 2021
• Doi Number: 10.5152/eurasianjmed.2021.20342
• Journal Name: EURASIAN JOURNAL OF MEDICINE
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
• Page Numbers: pp.127-131
• Keywords: Sepsis, agomelatine, tumor necrosis factor-alpha, nuclear factor-kappa B, MELATONIN RECEPTOR, ANIMAL-MODELS, MT2 RECEPTORS, SEPSIS, GENES
• Ataturk University Affiliated: Yes

Abstract

Objective: We designed an experimental model of sepsis in rats to investigate the effects of agomelatine (AGO) on lung tissues using molecular and histopathological methods.