miRNAs Expressions and Interaction with Biological Systems in Patients with Alzheimer's Disease. Using miRNAs as a Diagnosis and Prognosis Biomarker

Negoita S. I., Sandesc D., Rogobete A. F., Dutu M., Bedreag O. H., Papurica M., ...Daha Fazla

CLINICAL LABORATORY, cilt.63, sa.9, ss.1315-1321, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 63 Sayı: 9
  • Basım Tarihi: 2017
  • Doi Numarası: 10.7754/clin.lab.2017.170327
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1315-1321
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background: A high percentage of patients develop Alzheimer's disease (AD). The main signs are loss of memory and cognitive functions which have a significant impact on lifestyle. Numerous studies have been conducted to identify new biomarkers for early diagnosis of patients with AD. An ideal biomarker is represented by the expression of miRNAs. In this paper, we want to summarize expressions miRNAs in AD. We also want to present the pathophysiological and genetic interactions of miRNAs with protein systems in these patients.