Effects of Autogenous Tooth Bone Graft and Platelet-Rich Fibrin in Peri-Implant Defects: An Experimental Study in an Animal Model

Kızıldağ A., Taşdemir U., Arabacı T., Kızıldağ C., Albayrak M., Sahin B.

JOURNAL OF ORAL IMPLANTOLOGY, cilt.46, sa.3, ss.221-226, 2020 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1563/aaid-joi-d-19-00038
  • Dergi Adı: JOURNAL OF ORAL IMPLANTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.221-226
  • Anahtar Kelimeler: bone formation, bone-implant interface, tooth graft, peri-implant defect, platelet-rich fibrin, CALCIUM-PHOSPHATE CERAMICS, GROWTH-FACTORS, DENTIN MATRIX, EXTRACTION SOCKETS, REGENERATION, EXPRESSION, PLACEMENT
  • Atatürk Üniversitesi Adresli: Evet

Özet

The aim of this study was to evaluate the effect of autogenous tooth bone graft (ATBG) combined with platelet-rich fibrin (PRF) on bone healing in rabbit peri-implant osseous defects. Eighteen New Zealand rabbits were divided into 3 groups. Bone defects were prepared in each rabbit, and then an implant cavity was created in the defects. Dental implants were placed, and the peri-implant bone defects were treated with the following 3 methods: no graft material was applied in the control group, bone defects were treated with ATBG in the ATBG group, and bone defects were treated with ATBG combined with PRF in the ATBG+PRF group. After 28 days, the rabbits were sacrificed, and the dental implants with surrounding bone were removed. New bone formation and the percentage of bone-to-implant contact (BIC) were determined with histomorphometric evaluations. New bone formation was significantly higher in the ATBG+PRF group than the control and ATBG groups (P< .05). In addition, BIC was significantly higher in the ATBG+PRF group than in the control and ATBG groups (P< .05). The combination of ATBG with PRF contributed to bone healing in rabbits with peri-implant bone defects.