Epigallocatechin-3-gallate (EGCG) exert therapeutic effect on acute inflammatory otitis media in rats

KAYA Z., YAYLA M., Cinar I., Atila N. E., ÖZMEN S., BAYRAKTUTAN Z., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.124, pp.106-110, 2019 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 124
  • Publication Date: 2019
  • Doi Number: 10.1016/j.ijporl.2019.05.012
  • Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.106-110
  • Keywords: EGCG, Inflammation, LPS, Otitis media, Rat, ALPHA, LIPOPOLYSACCHARIDE, VIRULENCE, ACID
  • Ataturk University Affiliated: Yes

Abstract

Introduction: That EGCG has strong antioxidant and anti-inflammatory activities as well as antibacterial activity against many streptococcus species suggests that it may be beneficial in the treatment of AOM. Objective: Aim of the study is to reveal the molecular and biochemical effects of EGCG on LPS induced otitis media in rats.