Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation


KANDEMİR F. M. , ÇAĞLAYAN C., DARENDELİOĞLU E., KÜÇÜKLER S. , Izol E., Kandemir O.

LIFE SCIENCES, vol.277, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 277
  • Publication Date: 2021
  • Doi Number: 10.1016/j.lfs.2021.119610
  • Title of Journal : LIFE SCIENCES

Abstract

Aim: Cadmium (Cd) is a toxic heavy metal that causes severe toxic effects on different tissues including liver and kidney. Therefore the research for alternatives to reduce the damage caused by Cd has substantial importance. This study was performed to examine the possible modulatory effects of carvacrol (CRV) against Cd-induced hepatorenal toxicities and the possible mechanisms underlying these effects.