Comparison of unilateral and bilateral microdissection testicular sperm extraction (MD-TESE) in patients with non-obstructive azoospermia: a prospective study


Utlu A., Ozkaya F., Aksakalli T., Cinislioglu A. E., DEMİRDÖĞEN Ş. O., Altay M. S., ...Daha Fazla

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.55, sa.9, ss.2177-2182, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 9
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s11255-023-03668-0
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, Gender Studies Database
  • Sayfa Sayıları: ss.2177-2182
  • Anahtar Kelimeler: Azoospermia, Bilateral, Inhibin B, Microdissection, Unilateral, Testicle, PREDICTIVE FACTORS, INJECTION, RECOVERY, BIOPSY
  • Atatürk Üniversitesi Adresli: Evet

Özet

ObjectiveTo compare sperm retrieval rates between unilateral and bilateral microdissection testicular sperm extraction (MD-TESE) procedures in patients with non-obstructive azoospermia and to contribute to the literature by comparing them with literature data.MethodsThis prospective study included 84 males with primary infertility who had azoospermic NOA, who had been married for at least one year, and whose female partners did not have a history of infertility. The study was conducted between January 2019 and January 2020. MD-TESE was applied bilaterally to 48% (n:41) (Group 1) and unilaterally to 52% (n:43) (Group 2) of the patients, and sperm retrieval rates were compared.ResultsThere was no statistically significant difference between Group 1 patients and Group 2 patients in terms of sperm availability (61%, 56.5%, p=0.495, respectively). In addition, while no complications were observed in unilateral MD-TESEs, 3 complications were observed in bilateral MD-TESEs.ConclusionsIn our study, it was determined that there was no significant difference between the groups in terms of sperm availability in patients with NOA. Considering the operative time and complication rates of bilateral MD-TESE in patients diagnosed with NOA and the possible MD-TESE procedures that may be performed later, we believe that unilateral MD TESE is a more preferable procedure for the patient and surgeon in this patient group.