Effects of Botulinum Toxin A Injection on Ambulation Capacity in Patients with Cerebral Palsy


Okur S. C., UĞUR M., Senel K.

DEVELOPMENTAL NEUROREHABILITATION, cilt.22, sa.4, ss.288-291, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/17518423.2018.1502832
  • Dergi Adı: DEVELOPMENTAL NEUROREHABILITATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.288-291
  • Anahtar Kelimeler: Ambulation, botulinum toxin A, cerebral palsy, spasticity, CLASSIFICATION, MANAGEMENT, SPASTICITY, DEFINITION, CHILDREN, ADULTS
  • Atatürk Üniversitesi Adresli: Evet

Özet

Purpose: The purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy. Methods: Thirty patients with CP, 3-13 years who had varied functional levels and lower extremity spasticity, were randomized in two groups. In Group 1(n = 15), BoNT-A was administered to the affected extremity and underwent rehabilitation. In Group 2 (n = 15), the patients underwent only rehabilitation protocol. The Visual Analogue Scale (VAS), Tardieu Scale (TS), Gross Motor Function Classification System (GMFCS), Selective Motor Control, and Goal Attainment Scale were evaluated 4 and 12 weeks after baseline. Results: The mean scores of the TS (p < 0.001) GMFCS, GAS, and VAS (p < 0.05) significantly improved in Group 1. Conclusion: We think that implementation of rehabilitation protocols with BoNT-A injection is superior to alone rehabilitation therapy and increasing ambulatory capacity in patients with CP.