In vitro effects of some drugs on human erythrocyte glutathione reductase.

AKKEMİK E., Senturk M., ÖZGERİŞ F. B., Taser P., Ciftci M.

Journal of enzyme inhibition and medicinal chemistry, vol.27, no.2, pp.18-23, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.3109/14756366.2011.572879
  • Journal Name: Journal of enzyme inhibition and medicinal chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.18-23
  • Keywords: Glutathione reductase, dacarbazine, thiocolchicoside, methotrexate, RAT ERYTHROCYTES, AFFINITY-CHROMATOGRAPHY, ENZYME-ACTIVITIES, PURIFICATION, ANTIBIOTICS, GLUCOSE-6-PHOSPHATE-DEHYDROGENASE, INHIBITION, METABOLISM, CLEAVAGE, LIVER
  • Ataturk University Affiliated: Yes

Abstract

Aim: The effects of dacarbazine, thiocolchicoside, methotrexate, olanzapine, pantoprazole sodium, and 5-fluorouracil on the enzyme activity of glutathione reductase (GR) were studied using human erythrocyte GR enzymes in in vitro studies, respectively.