Morin attenuates acrylamide-induced testicular toxicity in rats by regulating the NF-kappa B, Bax/Bcl-2 and PI3K/Akt/mTOR signaling pathways


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Küçükler S. , Caglayan C., Darendelioğlu E., Kandemir F. M.

LIFE SCIENCES, vol.261, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 261
  • Publication Date: 2020
  • Doi Number: 10.1016/j.lfs.2020.118301
  • Title of Journal : LIFE SCIENCES

Abstract

Aim: Acrylamide (AC) is a carcinogenic substance which is formed during the heating of starchy foods at high temperatures and constitutes an important risk for human health. Therefore, reducing the detrimental effects of AC has become an important research topic. This study was performed to evaluate the protective effect of morin against the testicular toxicity induced by AC in male rats.