Novel halo-molecules; synthesis, structure elucidation, mechanism, and antioxidant activity

Bekfelavi E. Y., YILMAZ Ö., ŞAHİN E., ŞİMŞEK KUŞ N.

MONATSHEFTE FUR CHEMIE, cilt.152, sa.2, ss.295-304, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 152 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s00706-021-02746-2
  • Dergi Adı: MONATSHEFTE FUR CHEMIE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core
  • Sayfa Sayıları: ss.295-304
  • Anahtar Kelimeler: Antioxidant properties, DPPH (2,2-diphenyl-1-picrylhydrazyl), Haloalcohol, Haloepoxy, Haloketone, Halolactone
  • Atatürk Üniversitesi Adresli: Evet

Özet

In this study, haloepoxy, haloketones, halolactones, haloaldehydes, and haloalcohols which may have biological importance have been synthesized from ketene addition reactions. The structures of the molecules were illuminated by NMR, especially the COSY spectroscopy. In addition, FT-IR and GC-MS techniques were used. While doing the synthesis, we surprisingly encountered the quasi-Favorskii arrangement product. X-ray analysis was performed to determine the exact structure of this molecule. Furthermore, the antioxidant properties of some molecules were investigated and compared to standards (BHT, BHA, and alpha-tocopherol).