mFOLFOX-based Chemotherapy Can Augment Survival in Advanced Gastric Cancer Patient with Disseminated Intravascular Coagulation

Aldemir M. N., Turkeli M., Simsek M., Cayir K., Yildirim N., Bilici N. M., ...Daha Fazla

WEST INDIAN MEDICAL JOURNAL, cilt.69, sa.7, ss.520-522, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 7
  • Basım Tarihi: 2022
  • Doi Numarası: 10.7727/wimj.2015.271
  • Dergi Adı: WEST INDIAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.520-522
  • Anahtar Kelimeler: Advanced gastric cancer, disseminated intravascular coagulation, mFOLFOX-based chemotherapy, 5-FLUOROURACIL
  • Atatürk Üniversitesi Adresli: Evet

Özet

Although gastric cancer is a frequent cancer type, disseminated intravascular coagulation is a very rare but serious complication of this disease. We report a 65-year-old man who complained of weight loss, nausea and vomiting, fatigue and dyspnoea for three days. He was diagnosed as having advanced gastric cancer complicated with disseminated intravascular coagulation, which was successfully treated with mFOLFOX chemotherapy regimen. After one cycle of mFOLFOX therapy, thrombocytopenia was improved and serum lactate dehydrogenase levels decreased. Remarkable remission was seen. After 12 cycles of chemotherapy, remarkable remission was seen in the primary tumour and multiple metastatic bone lesions.