Is perforated marginal ulcer after the surgery of gastroduodenal ulcer associated with inadequate treatment for Helicobacter pylori eradication?

Aydinli B., Yilmaz O., Ozturk G., Yildigan M. I., Gursan N., Basoglu M.

LANGENBECKS ARCHIVES OF SURGERY, cilt.392, sa.5, ss.593-599, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 392 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/s00423-007-0167-4
  • Dergi Adı: LANGENBECKS ARCHIVES OF SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.593-599
  • Atatürk Üniversitesi Adresli: Evet

Özet

Background and aims A marginal ulcer developing after an initial operation for gastroduodenal ulcer is a serious threat to the patient, and a challenge to surgeons. Helicobacter pylori is the primary cause of peptic ulcer disease. However, its role in ulcer recurrence, especially of marginal ulcer (MU), after peptic ulcer surgery is unclear. This study aimed to determine any association between H. pylori infection and perforated MU by comparing the prevalence of H. pylori and nonsteroidal anti-inflammatory drugs (NSAIDs) use in patients with perforated (PMU) and in those with nonperforated MU (NPMU).