Chemical and morphological characterization of allium tuncelianum (amaryllidaceae) and its antioxidant and anticholinesterase potentials

KARAKAYA S. , Eksi G., KOCA M. , Demirci B., KAYMAK H. Ç. , Kaplan M. E. , ...More

Anales del Jardin Botanico de Madrid, vol.76, no.2, pp.1-7, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.3989/ajbm.2523
  • Title of Journal : Anales del Jardin Botanico de Madrid
  • Page Numbers: pp.1-7


Alzheimer's disease is the main reason for dementia, which increases with age. Cholinesterase inhibition and antioxidant potentials of extracts and essential oils from bulbs of A. tuncelianum (Kollmann) Ozhatay & al., an endemic species to Tunceli (easthern Turkey), were evaluated. The fraction extracted of ethyl acetate had the highest phenolics level, 1,1-diphenyl-2-picrylhydrazyl, and thiobarbituric acid antioxidant capacity. Also, the ethyl acetate fraction presented the highest acetylcholinesterase (15.98 +/- 2.76%), and butyrylcholinesterase inhibition (47.33 +/- 3.27%). Diallyl disulfide (49.8%), diallyl trisulfide (27.9%) and allyl methyl trisulfide (6.9%) were found to be the major components of essential oil. This paper shows that the ethyl acetate fraction of A. tuncelianum could be a potent source of antioxidant and anticholinesterase components.