Meso-piperidine linked bodipys: Synthesis, fluorescent properties and biological evaluation

Eçik E., Kazan H. H., Sengul I. F., Kandemir H., Çoşut B.

Journal of Luminescence, vol.205, pp.258-264, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 205
  • Publication Date: 2019
  • Doi Number: 10.1016/j.jlumin.2018.09.024
  • Journal Name: Journal of Luminescence
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.258-264
  • Ataturk University Affiliated: No

Abstract

The synthesis and characterization of meso-piperidine linked Bodipy starting from 4-(2-(piperidine-1-yl)ethoxy) benzaldehyde was described. Meso-piperidine linked Bodipy was subsequently used for the construction of distyryl-piperidine-Bodipy and distyryl-morpholine-Bodipy via Knoevenagel type reaction. The photophysical properties including molar extinction coefficient, fluorescence lifetime and fluorescence quantum yield of Bodipys were investigated in ethanol solution. The targeted compounds were also assessed in live cell imaging and cytotoxicity studies by using breast cancer cell line, MCF-7 in vitro.