KIRIM KONGO KANAMALI ATEŞİ TANISIYLA İZLENEN HASTALARIN EPİDEMİYOLOJİK VE BİYOKİMYASAL OLARAK DEĞERLENDİRİLMESİ


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PARLAK E., KESMEZ CAN F., ALAY H., PARLAK M., ÖZKURT Z., KOŞAN Z.

JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH, cilt.4, sa.3, ss.320-327, 2020 (Hakemli Dergi)

Özet

Aim Crimean-Congo Hemorrhagic Fever (CCHF) is a viral hemorrhagic fever. To evaluate the clinical, epidemiological and laboratory characteristics of patients with CCHF. Methods  is study was performed with adult patients under monitoring with diagnosis of CCHF at the Atatürk University Faculty of Medicine Infectious Diseases Clinic between April 2012 and August 2013. Results Diagnosis of CCHF was based on presence of Enzyme-linked immunosorbent assay (ELISA) anti-CCFV IgM and/or virus antigen at Refik Saydam Hygiene Center (RSHM) in patient serum and/or real time Polymerase Chain Reaction (PCR). One hundred twenty-one cases were included. Fi y-eight (48.7%) of patients were male and 62(51.2%) female, with a mean age of 50.04 ± 18.22 (16-86) years. Contact with ticks was determined in 62.8% of patients. Length of incubation was 3.9±2.7 days. Five patients (4.1%) died. Conlusion CCHF which is carried by ticks is a fatal viral infection.  e most important factor in protection is the prevention of tick contact. People living in endemic regions must be educated and instructed how to perform daily tick checks. Patients have got high fever, myalgia, headache and tick bite must be asked in history. We believe that early diagnosis and treatment of CCHF cases may significantly reduce morbidity and mortality.

Key words Crimean-Congo Hemorrhagic Fever, mortality rate, Turkey