Modular Synthesis of Planar-Chiral para-Substituted Paracyclophanes by Double Suzuki Coupling

Cakici M., BRAESE S.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no.31, pp.6132-6135, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2012
  • Doi Number: 10.1002/ejoc.201201043
  • Journal Name: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.6132-6135
  • Keywords: Cyclophanes, Cross-coupling, Chirality, Boron, Hydrocarbons, MACRO RINGS, DERIVATIVES
  • Ataturk University Affiliated: Yes

Abstract

The first synthesis of enantiomerically pure 4,7-paracyclophane ditriflate starting from a quinone was reported. Using this molecule, mono- or dicoupling with boronic acids delivered enantiomerically pure arylparacyclophanes.