The association of human leukocyte antigenpolymorphisms with disease severity and latencyperiod in patients with silicosis


DOĞAN H. , AKGÜN M. , ARAZ Ö. , YILMAZEL UÇAR E. , YÖRÜK Ö. , BALKAN E. , ...More

Multidisciplinary Respiratory Medicine, vol.9, pp.1-6, 2014 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9
  • Publication Date: 2014
  • Doi Number: 10.1186/2049-6958-9-17
  • Title of Journal : Multidisciplinary Respiratory Medicine
  • Page Numbers: pp.1-6

Abstract

Background: Denim sandblasting may cause silicosis as a result of free crystalline silica inhalation. Its pathogenesis remains unclear, but autoimmunity may play a role in the development of silicosis. The present study aimed to investigate the relationships between human leukocyte antigen (HLA) and the severity and latency period of silicosis.