Low-grade tubulopapillary adenocarcinoma of sinonasal tumors: Diagnosis and follow-up


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Miloğlu Ö., Naralan M. E., Derindağ G., Şipal S.

Türkiye Klinikleri Diş Hekimliği Bilimleri Dergisi, cilt.27, sa.4, ss.704-709, 2021 (Hakemli Dergi)

Özet

ABSTRACT

Low grade tubulopapillary adenocarcinoma is one of the rare sinonasal tumors. A 65-year-old male patient was admitted to our clinic with painless intraoral and extraoral swelling and speech disorder. Radiological examination of the patient revealed a lesion suggesting malignancy. The area of ​​the lesion spread from the left maxillary area to the maxillary sinus, nasal cavity, zygomatic bone and the base of the eye, causing resorption of the bones in the regions. As a result of biopsy, the lesion was diagnosed as well-differentiated low-grade tubulopapillary adenocarcinoma. The patient was referred to the oncology department of the medical faculty and the radiotherapy was started by the medical faculty board, indicating that it was not suitable for surgical treatment. After 1.5-year follow-up, the patient was re-biopsied and diagnosed as poorly differentiated tubulopapillary adenocarcinoma. We think that the aggressive lesion may show heterogeneous differentiation as a possible reason for the differentiation between the two biopsies.

Keywords: low grade tubulopapillary adenocarcinoma; sinonasal tumors; ultrasonography; magnetic resonance imaging