HUMAN HIV-1 TAT-INTERACTIVE PROTEIN 2 AS A PROGNOSTIC AND/OR DIAGNOSTIC FACTOR FOR ANKYLOSING SPONDYLITIS, RHEUMATOID ARTHRITIS AND SARCOIDOSIS

UZKESER H., ÇADIRCI E., HALICI Z., Aydin S., ÖZKANLAR S., ARAZ Ö., ...Daha Fazla

ACTA MEDICA MEDITERRANEA, cilt.31, sa.1, ss.115-120, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 1
  • Basım Tarihi: 2015
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.115-120
  • Anahtar Kelimeler: Ankylosing spondylitis, rheumatoid arthritis, sarcoidosis, HTATIP2/TIP30, SYSTEMIC-LUPUS-ERYTHEMATOSUS, POPULATION-BASED COHORT, AUTOIMMUNE-DISEASES, CANCER INCIDENCE, TIP30, RISK, MALIGNANCY, METASTASIS, LYMPHOMA, MORTALITY
  • Atatürk Üniversitesi Adresli: Evet

Özet

Introduction: Some chronic inflammatory or autoimmune conditions and various cutaneous granulomatous disorders are associated with an increased occurrence of malignancies. Human HIV-1 TAT-Interactive Protein 2 (HTATIP2/TIP30), also called TIP30 or CC3, is expressed in human tissues and some tumor tissues. Therefore, HTATIP2/TIP30 can be a possible target for early diagnosis, prediction of prognosis, and/or treatment of rheumatoid arthritis (RA), ankylosing spondylitis (AS) and sarcoidosis co-morbid malignancies.