Peritonitis Incidence is Correlated with Increased Leptin and CD4/CD8 Ratio in Peritoneal Dialysis Patients


Bilen Y. , ÇANKAYA E. , Bilen N. , UYANIK A. , ERDEM F. , UYANIK M. H.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.24, no.3, pp.307-311, 2015 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5262/tndt.2015.1003.10
  • Title of Journal : TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Page Numbers: pp.307-311

Abstract

Peritonitis is one of the leading cause of hospitalization in peritoneal dialysis patients. Although inflammatory markers show an increased inflammatory response, cellular immune response is decreased in ESRD patients. Uremia has many affects on leptin and T lymphocytes that are basic elements of the cellular immune system. In this study, we aimed to demonstrate the relationship between peritonitis and the CD4, CD8 positive lymphocyte count and ratio, and serum leptin level in peritoneal dialysis patients.