Research Information System
ICENS, Sarejova, Bosnia And Herzegovina, 24 May 2016, pp.129
In this study, it is aimed to produce biocompatible microelectrodes which can be used in the detection of neurotransmitters that are related with brain disorders such as Parkinson, Epilepsy, and Schizophrenia and that exist in the central nervous system (CNS). For this purpose, a new four-channel Ceramic-based microelectrode was fabricated by using photolithographic methods and it is tested in hydrogen peroxide. The time-current graphic response against the addition of H2O2 the produced microelectrode is analyzed in the calibration test. It is observed that the response is in stepwise form. We observed significant improvements in terms of Limits of detection (LOD) and linearity (R2) values, which are the parameters that determine the quality of the microelectrode. The value of R2 and LOD are obtained about 0.999 and between (0.1 - 0.5) respectively, which are the desired values for detection applications. The value of R2 which is very close to one shows that the response of the microelectrode against to peroxide is very good, and the value of LOD which is being in between (0.1 - 0.5) denotes that the fabricated microelectrode is robust against the environmental noise and it produce stable response.