Thirty-six month results from a prospective randomized study: Cyanoacrylate glue closureversus laser ablation for refluxing great saphenous veins


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Çalık E., Usta H., Erkut B.

TÜRK KALP VE DAMAR CERRAHİSİ DERNEĞİ 17. KONGRESİ, Antalya, Türkiye, 17 Kasım 2022, cilt.30, ss.44

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 30
  • Basıldığı Şehir: Antalya
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.44
  • Atatürk Üniversitesi Adresli: Evet

Özet

BACKGROUND AND AIM:The use of endovenous cyanoacrylate ablation (CAA), which is one of the new techniques in the treatment of symptomatic venous insufficiency, has become increasingly common worldwide. We aimed to evaluate the 36-month efficacy and safety of CAA for the treatment of refluxing great saphenous veins in comparison with endovenous laser ablation (EVLA).

METHODS:In this prospective randomized study, 400 patients with refluxing great saphenous veins were assigned to either CAA or EVLA. In their third year follow-up, physical examination and duplex ultrasound were performed; venous clinical severity scores and quality of life questionnaires were evaluated by the investigators. Overall success rates at 36 months were compared.

RESULTS:Of 400 randomized subjects, 316 completed the 36-month follow-up, which were 159 in the CAA group and 157 in the EVLA group. The complete closure rate was 93.8% in the CAA group and 91.2% in the EVLA group based on month 36. The improvement in symptoms and quality of life was the same in both groups and increased, though at a slower pace. Device or procedure-related late side effects were not observed in either group.

CONCLUSIONS:Based on 36 months follow-up, this study showed that the efficacy and safety of CAA in the menagement of refluxing great saphenous veins was similar to EVLA and non-inferior to EVLA with high closure rate. The improvement in clinical and quality of life results were continued in both treatment modalities and were found to be similar.

 

 

Keywords: Endovenous cyanoacrylate ablation